Plasma sex hormone binding globulin in patients with prostatic carcinoma
نویسندگان
چکیده
منابع مشابه
Alternative ELISA for sex hormone-binding globulin in plasma.
To the Editor: Bioavailable testosterone is often derived from the free androgen index (1), which is reliant on measurements of both testosterone and sex hormone-binding globulin (SHBG). Although testosterone assays are widely available in various formats, assays for SHBG are more restricted partly because of the absence of automated procedures and the relatively high expense of kits. Dako (Den...
متن کاملSerum sex steroids, gonadotrophins and sex hormone-binding globulin in prostatic hyperplasia.
BACKGROUND Benign prostatic hyperplasia (BPH) develops in elderly males when serum androgens are relatively lower than in healthy younger males, but it is not well understood whether and how sex steroids are altered in prostatic hyperplasia. It is also uncertain whether there is any change in sex steroid levels in males older than 40 years of age. The use of androgens in elderly males is often ...
متن کاملThe Evaluation of Serum Level of Testosterone and Sex Hormone- Binding Globulin in Men with Type 2 Diabetes
OBJECTIVE: To evaluate the relationship between serum level of testosterone and sex hormone-binding globulin in men with type 2 diabetes. MATERIALS AND METHODS: In this case-control study, forty men aged 40-70 with type 2 diabetes mellitus were randomly selected and compared with 40 non-diabetic men. The two groups were matched for their age and BMI. After complete observation and examination...
متن کاملDiet and sex hormone-binding globulin.
The serum concentration of sex hormone-binding globulin (SHBG) is inversely related to weight and in animal studies is inversely related to protein intake. As SHBG can affect the biological activity of testosterone and estradiol, we wished to determine the role of protein intake on SHBG levels in men. Using data from the Massachusetts Male Aging Study we examined cross-sectional relationships b...
متن کاملAssociation between the Asp327Asn Polymorphism of Sex Hormone-Binding Globulin Gene and Prostate Cancer
Background: By binding SHBG hormone to sex hormones, in addition to carrying them in the blood, they regulate the amount of tissue availability. Since the genetic changes in the structure of globulin affect it’s binding to hormones, so in this study the effects of single nucleotide change in exon 8 or rs 6259 in the incidence of prostate cancer is evaluated. Methods: The study populati...
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ژورنال
عنوان ژورنال: Cancer
سال: 1990
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19900715)66:2<354::aid-cncr2820660225>3.0.co;2-n